副教授

研究方向:等离子体技术及生物医学应用

电子邮箱:dehuixu@mail.xjtu.edu.cn

一、学习工作简历

20057月于西安交通大学获临床医学学士学位,同年保送硕士研究生。20087月获遗传学硕士学位。200810月公派赴比利时布鲁塞尔自由大学攻读博士学位,并于201212月获得医学生物学博士学位。回国后聘为西安交通大学学术特区讲师,201610月晋升西安交通大学副教授。

主要从事大气压冷等离子体生物医学应用,等离子体生物学机制研究及等离子体肿瘤治疗研究。主持国家自然科学基金等项目共10余项,主研国家自然基金重点项目、GF重点研发等项目。累计发表SCI论文40余篇,其中包括一篇LeukemiaIF=12.104)和一篇英文专著章节。授权发明专利5项。在亚太等离子体物理等国际会议上作关于等离子体癌症治疗方面的特邀报告6次。同时担任国家青年及地区科学基金评审人及国际杂志ACS Applied Materials & InterfacesJournal of Physics D: Applied Physics等审稿人。

二、代表性期刊论文

1.      D Xu, Y Xu, N Ning, et al. Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells. Cancer cell international. 2018,18,42.

2.        D Xu, Q Cui, X Xu, et al. Systemic study on the safety of immuno-deficient nude mice treated by atmospheric plasma-activated water. Plasma Sci Technol. 2018, 20(4).

3.        D Xu, Y Xu, Q Cui,et al. Cold atmospheric plasma as a potential tool for multiple myeloma treatment. Oncotarget. 2018,9(26):18002-17.

4.        Z Chen, Q Cui, CChen, et al. Inactivation of myeloma cancer cells by helium and argon plasma jets: The effect comparison and the key reactive species. PhysPlasmas. 2018, 25(2).

5.        D Xu, J Hu, E Bruyne, et al. Dll1/Notch activation accelerates multiple myeloma disease development by promoting CD138+ MM-cell proliferation. Leukemia.2012 Jun; 26(6):1402-5.

6.        D Xu, D Liu, B Wang,etal. In Situ Oh Generation from O2-and H2O2Plays a Critical Role in Plasma-Induced Cell Death. PloS one 2015, 10. 年度3万篇论文中引用次数前1%.

7.        D Xu, B Wang, Y Xu,et al. Intracellular ROS mediates gas plasma-facilitated cellular transfection in 2D and 3D cultures. Scientific reports 2016.

8.        D Xu, X Luo, Y Xu,et al. The effects of cold atmospheric plasma on cell adhesiondifferentiation, migration, apoptosis and drug sensitivity of multiple myeloma. Biochem Biophys Res Commun. 2016, 473, 1125-1132.

9.        D Xu, J Hu, E Bruyne, et al. Dll1/Notch activation contributes to bortezomib resistance by upregulating CYP1A1 in multiple myeloma. Biochem Biophys Res Commun.2012, 10, 071.

10.     许德晖*,崔庆杰,许宇静,.等离子体医学及其在肿瘤治疗中的应用.生物化学与生物物理进展. 2017, 44, 279-292.